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Following this reasoning, in April 2018, Lithuanias tobacco regulator fined a PMI subsidiary for advertising the IQOS device, determining the device is subject to the same advertising restrictions as other tobacco products74 based on its view that this device can only be used to smoke tobacco products.75 As of May 2018, PMI was promoting IQOS as a less harmful alternative to cigarettes.3 9 50 60 76 Because these claims have not been substantiated with scientific evidence, they violate FCTCs Article 11 and Article 13 prohibitions

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The reason for both episodes of carbon monoxide poisoning was heavy tobacco smoking, more than two packs a day

5 Conclusions In this study, we identified nine members of the tobacco PSY gene family and conducted bioinformatics analysis of these genes, including their gene structure, conserved domains, and expression patterns under different stresses

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