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Citation: Wertz MS, Kyriss T, Paranjape S, Glantz SA (2011) The Toxic Effects of Cigarette Additives
Other ingredients are brand-dependent but can generally be split into five categories: Fillers: Provide pouches with bulk and make them easier to handle and keep in your mouth Sweeteners: Make the pouches sweet without harming your teeth or spiking blood sugar Stabilizers: Maintain consistency within pouches and prevent clumping pH adjusters: Stabilize pH levels for enhanced efficiency and flavor Flavorings: Provide the pouches with various flavors The nicotine in pouches can be plant-derived or synthetic
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Most often, this will result in a condition called atherosclerosis characterized by plaque buildup in the arteries
PMID 22406732 "Nomenclature and classification of potentially malignant disorders of the oral mucosa"
Nonparametric Wilcoxon rank sum tests were used to compare mutation counts per patient in the four categories of smoking history
