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Furthermore, current smokers have been shown to have a higher HCC risk (HR = 2.46, 95% CI = 1.773.43) in a dose-dependent manner with the number of cigarettes smoked [104]

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Thorax 57 , 226230 (2002)

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Concerning skin barrier lipids, comparable contents of the major SC barrier lipid classes and also precursors of ceramides were found in both groups of volunteers, except for cholesterol sulfate and phospholipids, which were increased in smokers
