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Ther Drug Monit 2003;25(1):4653

It should be noted, however, that 6% COHb reduced skeletal muscle fatigue resistance 24 and the 3% COHb in our participants may not have had a measurable impact on the oxygen delivery to the skeletal muscle, and hence the fatigue resistance

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Doctors look for persistent breathing problems such as shortness of breath, dry cough, and wheezing that do not respond to typical asthma treatment