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Many people who would benefit from GLP-1 therapy never start or discontinue early because of needle aversion

These differences matter because one GLP-1 medicine should not be exchanged for another without clear clinical direction

Lancet 2021;398:262-76.ArticlePubMed 9

Also, one strain of gut bacteria, Akkermansia municiphilia , acts as probiotic that the brand says helps strengthen the gut lining, improves digestive health, and helps manage a healthy weight. Akkermansia also triggers the secretion of GLP-1

In addition, the medication is generally well-tolerated, with mild-to-moderate side effects such as nausea and diarrhea being the most common

For specific guidance on rate- and rhythm-control drugs such as beta-blockers, calcium channel blockers, amiodarone, and flecainide, see our guide on Mounjaro and heart rhythm medications