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In addition to the heterotypic cell-cell interaction with keratinocytes, MCs are in direct contact with the basement membrane, a specialized extracellular matrix (ECM) rich in type IV collagen (COL IV), which forms the junction with the underlying dermis, comprising type I collagen (COL I) and fibronectin (FN) (Pfisterer et al, 2021)

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Concentrated mineral medium with the C/N ratio of 60 (mol/mol) supplemented with glycerol was used for feeding at the flow rate profile according to the Eq

Assays for HCV RNA Qualitative Assays HCV RNA can be detected in the blood using amplification techniques such as polymerase chain reaction (PCR) or transcription- mediated amplification (TMA) 28