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The study included 390,929 adults, ages 25 to 74 years (average age of 47), 56% female

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It has been observed that older monozygotic twin pairs demonstrate greater DNA methylation differences than younger monozygotic twin pairs ( epigenetic drift might be due to the accumulation of small errors in copying DNA methylation marks during successive cell divisions ( epigenetic drift ( TISSUE-SPECIFICITY OF DNA METHYLATION PATTERNS A considerable similarity in DNA methylation levels exists across different tissues

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