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The troughs are higher, so appetite suppression should remain more consistent

The approval was supported by the Phase III VISIBLE 2 study, where a statistically significant proportion of patients receiving 108 mg of Entyvio SC maintenance therapy administered every two weeks achieved long-term clinical remission compared to the placebo group after 52 weeks

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Up Next: Sources: Pandey A., Ye, Yang, Wells, C.R., et al

March 11, 2019

Important safety considerations include a boxed warning for thyroid C-cell tumors (contraindicated in patients with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2), risk of pancreatitis, gallbladder disease, and acute kidney injury with dehydration