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There were similar rates of mild adverse events (e.g., nausea, restlessness, insomnia, irritability) across groups in trials of cytisine based on our initial overview.22 However, an updated Cochrane review on cytisine42 suggested there may be a small increase in adverse events, which could constitute a small harm (4 RCTs, n = 4052

So, if youre underage, we wish you the best, but your money is no good here

For heavy users chasing flavor and customization, yes

If you have deep vertical wrinkles around your mouth or severe hyperpigmentation, medical treatments may be a better option.

It may reduce appetite slightly but damages metabolism and overall health

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