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Higher risks were evident in individuals who had quit smoking and at high smoking intensities

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This effect was explained through activating CB2 receptors and subsequently reducing cyclin-dependent kinase-2 (Cdc2) levels, which makes the cell enter mitosis (Feng et al

10.1111/add.15385 [DOI] [PMC free article] [PubMed] [Google Scholar] 36.Caci G, Selya A, La Rosa GRM, Spicuzza L, Morjaria JB, Polosa R (2025) Respiratory effects of electronic cigarette use in individuals who never smoked: A systematic review

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