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In 2023, the prevalence of EC use was greater than cigarettes among adults aged 1824 years

Zirkle CL, Kaiser C (1964)

Insertions of the DTT-NIC1 family were associated with significant divergences in expression and tissue specificity between duplicated genes (Figure 2d), consistent with the hypothesis that the expansion of this TE family was a critical determinant of genome-wide re-wirings of gene regulation occurring post-duplication in these Nicotiana species

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In the U.S., smoking kills more people than cocaine, heroin, alcohol, fire, automobile accidents, homicides, suicides, and AIDS combined

doi: 10.4103/ijcm.IJCM_195_19