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Chemicals in cigarettes contribute to atherosclerosis which is hardening of the arteries which should have started to reverse

When tobacco use interferes with these or other medications, it can impact quality of life for the patient or increase the risk of stroke
Reumann MK, Schaefer J, Titz B

Recovering nicotines reputation would also provide a clear commercial benefit to tobacco companies, many of which are betting on smoke-free products as their future given global declines in smoking rates

When absorbed into the bloodstream, these compounds also cause narrowing and hardening of the blood vessels, which increases the risk of heart disease, stroke, and other cardiovascular diseases
