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Multivariable analyses adjusting for factors including age, sex, hypertension, body mass index (BMI), alcohol intake, cholesterol and exercise habits showed SHS exposure was significantly linked to a higher risk of both PUD and GERD

[45] Physical examination [edit] Careful medical history and physical examination is essential in separating dangerous from trivial causes of disease, and the management of chest pain may be done on specialized units (termed medical assessment units ) to concentrate the investigations

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Experimental studies in rat lungs on the carcinogenicity and dose-response relationships of eight frequently occurring environmental polycyclic aromatic hydrocarbons