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"They dry the leaves on a fire," Hagen says

Its audacious lines and terrain-based approach inspired a wave of designers to take more liberties, to play more aggressively with landforms, and to respect what chaos can bring

This underlines the need for well-designed studies with large sample sizes and sufficient statistical power to allow for meaningful and conclusive results

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For example, some who study tobacco in China say the Global Burden of Disease overestimates smoking deaths in that country, in part by not accounting for how much air pollution and occupational risks (like coal dust) contribute to deaths among smokers