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In the film's novelization, it is explained that Constantine comes from a Christian culture and he has a greater natural understanding of the power of Christian relics, which makes it easier for him to use the objects

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This War in the Store was triggered in 1993 when Philip Morris heavily discounted its Marlboro brand, and other tobacco companies followed suit to compete

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For example, inhibition of TLR9 activation using immune-regulatory oligodeoxynucleotides transforms macrophage plasticity into anti-inflammatory macrophages and suppresses atherosclerotic plaque formation 41)