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An interaction between smoking (ever/never) and the NAT2 slow acetylator genotype was found with OR 6.44, 95%CI 3.07, 13.52 in the presence of both risk factors and a significant attributable proportion due to interaction of 0.50[45]

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Age-specific SLT consumption was 2%, 14%, and 43% for the age groups of 1830, 3145, and 46 years, respectively

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If the issue is the sale of tobacco related products to Americas youth, the current regulations should be strictly enforced