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[201] [202] Natural analogues [edit] Natural analogues of nicotine, often found in plants or other biological sources, include anabasine (from Anabasis aphylla), anatabine (from tobacco), arecoline (from betel nut), cotinine (major metabolite of nicotine), cytisine (from Laburnum species), and epibatidine (from frog skin), among others

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The growing curiosity around its potential has been explored in Nixamide vs Nicotine Explained: What Vapers Need to Know, which outlines how this compound differs from nicotine in both chemistry and user experience

Anyone who spent any time outside that day could tell just how nasty the air was, but here's a bit of perspective to wrap your respiratory system around