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19 Its use is associated with adverse effects, including nausea, vomiting, nicotine addiction, periodontal disease, heat intolerance, impaired cardiac function, and an increased risk of pancreatic cancer

Many who choose this type of whole-leaf tobacco appreciate the ability to enjoy tobacco in its purest form, free from the additives and processing found in mass-produced cigarette blends

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But HPV-associated cancers are still often curable at this point

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