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CS-triggered inflammation is considered to play a central role in various pathologies by a mechanism that stimulates the release of pro-inflammatory cytokines

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In tumors carrying mutp53, ectopic expression of SLC7A11 promotes tumor resistance to drugs that induce ferroptosis, further suggesting that mutp53 sensitizes cancer cells to ferroptosis by inhibiting SLC7A11 [79]

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This medicine is believed to be safer than smoking

Notably, although e-cigarette vapor can deliver substantial nicotine levels to HNSCC cells, in contrast to conventional cigarette smoke, the oxidative stress component and the metabolic disruptions associated with the reductive state appear to be significantly diminished if not completely absent