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Our RNA-seq data showed that expression of 14 genes related to ribosome ( RPL30, RPL37A, RPS14, RPS19, RPL7A, RPS12, RPS11, RPL32, RPL10A, RPL 19, RPL35, RPS5, RPS21, and RPS 27 ) was significantly down-regulated in NHBE cells treated with with e-cig treatment except that expression of RPS29 was up-regulated (Table 4)

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Investigations for a very short time period in canine models and long-term cannulated mice exposed to concentrated air particles showed that hypertension was produced and that there was an indication of central sympathetic activation of the neuron system, presumably induced by neuro-inflammation in relation to the disclosure of PM 2.5 (190, 191)

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