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There is no evidence that NRT is harmful in pregnancy and licensed NRT medication is routinely used to aid cessation While patients may be prescribed varenicline or bupropion, the drug of choice is most likely to be varenicline unless there are medical contra-indications [footnote 53]

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doi: 10.1093/eurheartj/ehy340

The origins of the first tobacco seeds came in 1592 when the Spanish Galleon San Clemente docked in Manila Bay with 50 Kilos (110 lbs) of Cuban tobacco seed from Mexico, which was part of the Spanish trade route

Comparing Zyn Nicotine Pouches to Other Nicotine Products Zyn nicotine pouches are part of a broader market of nicotine products, each with its own set of benefits and drawbacks