alcohol and tobacco are considered gateway drugs Scare Tactics or the Real Deal? The gateway theory of drug

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Biochem Biophys Res Commun 509:514520 Normanno N, De Luca A, Bianco C, Strizzi L, Mancino M, Maiello MR, Carotenuto A, De Feo G, Caponigro F, Salomon DS (2006) Epidermal growth factor receptor (EGFR) signaling in cancer

It can be triggered by sinus infections, migraines, neurological conditions, or prolonged exposure to cigarette smoke

The same reason why its easier/faster to mix a teaspoon of sugar into a tea, then it is to mix a cube of sugar (An anology which may help you understand the why)

My friends say Im better-looking now than when I was younger

root and leaf proteins under low and high nitrogen supply levels were systematically analyzed by comparative proteomics 8 , to understand the changes in protein expression and abundance in roots and leaves under low nitrogen stress