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Metabolism and disposition kinetics of nicotine
Your heart begins to pump differently, and the blood flow to the capillaries decreases
Beyond respiratory effects, evidence from human studies indicates that exposure to SHS is associated with a range of non-respiratory outcomes, including cardiovascular disease, urinary tract cancers, and immune dysregulation

One U.S.-based survey of people with Parkinsons disease, published in NPJ Parkinsons Disease, found that about 1 out of 4 respondents had tried cannabis within the past six months
Myeloid dendritic cells induce Th2 responses to inhaled antigen, leading to eosinophilic airway inflammation

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