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Phase I metabolic genes and risk of lung cancer: multiple polymorphisms and mRNA expression

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Located in Italy, Germany, and France

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In men, studies have reported multivariable-adjusted hazard ratios (aHR) of 1.25 (95% CI 1.211.29) for those with 1019.9 pack-years and 1.36 (95% CI 1.301.42) for those exceeding 20 pack-years compared with non-smokers

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This is at odds with the opinion of health authorities such as the Office of the Surgeon General, the Federal Health Department and the World Health Organization (WHO)

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