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doi: 10.3892/mmr.2017.6377 34

Moreover, there could be an effect of confounding factors such as chronic illnesses, duration of infertility, and history of testicular surgery

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Zhang H, Menzies KJ, Auwerx J

The following serious adverse reactions with the use of COCs are discussed elsewhere in the labeling: Adverse reactions commonly reported by COC users are: Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to the rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice