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National Cancer Institute Centers for Disease Control and Prevention

Abbreviations AD: Alzheimers disease A: Amyloid-beta BMI: Body mass index CIs: Confidence intervals DE: Direct effect DTI: Diffusion tensor imaging D1NMDA: D1NmethylDaspartate FA: Fractional anisotropy FEV1: Forced expiratory volume in one second FMRIB: Functional MRI of the Brain FSL: FMRIB Software Library FTD: Frontotemporal dementia GRN: Progranulin HDS: Healthy diet scores HNC: Higher national certificates HND: Higher national diplomas HRs: Hazard ratios IE: Indirect effect KDM-BA: KlemeraDoubal method biological age LTL: Leukocyte telomere length MAPT: Tau microtubule-associated proteins MD: Mean diffusivity mGluR2: Metabotropic glutamate 2 receptor MRI: Magnetic resonance imaging RCS: Restricted cubic spline SII: Systemic inflammatory index TDI: Townsend deprivation index T/S ratio: Ratio of telomere repeat number (T) to that of a single-copy gene (S) UKB: UK Biobank VD: Vascular dementia References Scheltens P, De Strooper B, Kivipelto M, Holstege H, Chtelat G, Teunissen CE, Cummings J, van der Flier WM