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Targeting Oncogenic Mutant p53 for Cancer Therapy
Levelling-off of the risk of lung and bladder cancer in heavy smokers: an analysis based on multicentric case-control studies and a metabolic interpretation
On the one hand, activated p53 can enhance autophagy by directly inducing the expression of autophagy genes
ACR, MVK and CPO are unsaturated carbonyl compounds that cause DNA damage and depletion of glutathione, an endogenous ROS scavenger [5]
Smoke is smoke, Ferdinand says
In the nucleus, AIF orchestrates cleavage of genomic DNA into large fragments resulting in cell death
