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Over 24 weeks, participants used an e-cigarette device filled with either 0, 8 or 36 milligrams per milliliter of liquid nicotine or a plastic tube (shaped like a cigarette) that delivered no nicotine or aerosol

For example, the researchers said, e-cigarettes include some of the same carbonyl compounds and toxic metals that are known to be carcinogenic and are also found in conventional cigarettes