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While peptides themselves are not inherently addictive, their misuse or overuse can potentially lead to dependency or addiction-like behaviors

Near-normoglycemia, with meaningful discontinuations of prandial insulin, by adding weekly albiglutide (Albi) to uncontrolled basal/bolus insulin-treated type 2 diabetes (T2DM) Diabetes

2004 Apr 29 Fujimoto K-i, Yoshida M, Ikeguchi K, Niijima K (1989) Impairment of active avoidance produced after destruction of pedunculopontine nucleus areas in the rat

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They form when the injection is administered too quickly and the solution pools rather than dispersing