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In 2011, the FDA drafted a guidance document (15) that was intended to help e-cigarette manufacturers submit ( a ) documentation of substantial equivalence (SE) if the product was similar enough to a tobacco product already on the market, or ( b ) a premarket tobacco product application (PMTA) if the product was substantially different

The cooperatives commitment to its members includes a dedication to industry innovation, which inspired them to support the North Carolina Plant Sciences Initiative (N.C