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Those numbers are smaller than Wegovy or Zepbound, but Saxenda still delivers clinically meaningful weight loss, and it is well-studied across a broad population including adolescents from age 12

The SELECT trial enrolled a specific population - adults with pre-existing cardiovascular disease - so this finding applies directly to that population

In a phase 2 trial, 43% to 100% of participants experienced at least a 50% reduction in liver fat, and 32% to 93% achieved at least a 70% reduction

The standard chemicals included acetic acid, propionic acid, butyric acid, isobutyric acid, pentanoic acid, isovaleric acid, and 2-methyl valerate

The glucagon component of retatrutide appears to drive this effect, as glucagon promotes hepatic fat oxidation, essentially telling the liver to burn its own stored fat