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The most common active compounds in cigarettes are nicotine and carbon monoxide
Some of the other cancer-causing agents found in chewing tobacco are formaldehyde, acetaldehyde, arsenic, benzopyrene, nickel, and cadmium
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Pregnancy: nicotine sensitivity often increases during pregnancy (oestrogen-induced CYP2A6 upregulation produces faster nicotine metabolism but more side effects)
Cancers linked to tobacco use make up 40% of all cancers diagnosed
Article: Spatiotemporal heterogeneity of gestational syphilis in the 1st Health Region of
