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Additional experimental and clinical studies will lead to a better understanding of the underlying molecular mechanisms of the regulation of endothelial function in response to single, short-term, and long-term exposure to cigarette smoke and next-generation tobacco and nicotine products

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Cyp1B1 mRNA expression in correlation to cotinine levels with respect to the Cyp1B1 L432V gene polymorphism

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So, a 10ml bottle at 12mg/ml (or 1.2%) has 120mg of nicotine in the whole 10ml bottle, or 1.2% of the liquid is nicotine