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Understanding these interactions and your individual risk profile helps support safer, more coordinated treatment decisions with your healthcare provider

The most striking protective effects of SGLT2is were a marked reduction in hospitalization for heart failure and a remarkable reduced progression of chronic kidney disease

Choosing glucose-lowering medication for patients with indicators of high risk or established ASCVD, CKD, or HF

**Functional Screening:** * The 10,000 designed GLP-1RAs underwent virtual screening based on stability, efficacy, and diversity criteria, which narrowed down the candidates to 60

Very few include older adults at high risk

Ingredients: CRUST (ENRICHED FLOUR [WHEAT FLOUR, NIACIN, REDUCED IRON, THIAMINE MONONITRATE, RIBOFLAVIN, FOLIC ACID], WATER, YEAST, SOYBEAN OIL, SUGAR, SOLUBLE CORN PRODUCT, DEHYDRATED GARLIC), REDUCED FAT MOZZARELLA CHEESE (CULTURED PART SKIM MILK AND SKIM MILK, MODIFIED CORNSTARCH*, SALT, VITAMIN A PALMITATE, ENZYMES, *INGREDIENT NOT IN REGULAR MOZZARELLA CHEESE), WATER, TOMATO PASTE, LOW-MOISTURE PART-SKIM MOZZARELLA CHEESE (CULTURED PART-SKIM MILK, SALT, ENZYMES), 2% OR LESS OF PARMESAN, ASIAGO AND ROMANO CHEESE BLEND (CULTURED PART-SKIM COW'S MILK, SALT, ENZYMES), MALTODEXTRIN, SUGAR, SALT, MODIFIED CORNSTARCH, DRIED GARLIC, SPICES, ONION POWDER