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No nicotine

adults whose highest level of education was a general educational development (GED) certificate

For example, youth initiation is closely correlated with having a parent who smokes, so helping adults to quit is critical to prevent young people from starting

impairment of genomic imprinting (lasting methylation of a subset of genes, many of which are associated with brain development and function)

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The behavioral symptoms of tobacco addiction are explained as follows: Frequent smoking or tobacco use despite a desire to quit