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Activation of microglia and iron accumulation in APP/PS1 mice has been associated with neuroinflammation and A aggregation (McIntosh et al., 2019)

Andrographolide, a ladanditerpene extracted from Andrographis paniculata, is a MAPK/Nrf2 pathway activator (Yang et al., 2017)

TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis

Three main mechanisms leading to hyperhomocysteinemia are these: (1) an inhibition of the homocysteine remethylation pathway dependent on folate or cobalamin deficiency, on the C677T mutation of MTHFR, or on the functional deficiency in methionine synthase