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On average, the total teenage population saw a decline in tobacco use from 12.3 % in 2011 to 7.8 % in 2016 , reflecting an overall reduction in smoking habits among Mexican teens over the five years

In 1998, an accord called the Master Settlement Agreement reached between 52 state and territory attorneys general resulted in millions of internal tobacco industry documents being made publicly available

These changes in response underlie the development of dependence, and they can lead to temporary withdrawal symptoms when one tries to quit

One notable example is the study of Fu et al

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