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Planta Medica 2006;72(4):37882
Results from a systematic review and metaanalysis

In particular, CYP1A1 and 2E1, although playing a minor role in the overall metabolism, can be induced by PAHs making smokers more prone to severe ADRs (e.g., QT prolongation) due to increased metabolite concentrations

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Depression and depressive symptoms in smoking cessation
