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Expert advice and tips from Mayo Clinic

Volkow and her colleagues reviewed the literature on pathophysiological processes that may hasten aging and are particularly relevant to smoking, second hand smoke, drug use, and addictions.6 They focused on oxidative stress and cellular aging, inflammation in periphery and brain, decline in brain volume and function, and early onset of cardiac, cerebrovascular, kidney, and liver disease

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Financial factors Start-up and ongoing costs Participants regularly expressed concerns that start-up costs of IQOS discouraged initiation