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In osteosarcoma, p53 R273H mutant reduces expression of procaspase-3, resulting in failure of chemotherapeutic agents such as methotrexate and doxorubicin to induce apoptosis [108]
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Scientists have known for hundreds of years that certain traits tend to run in families

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Gillings School of Global Public Health contact: David Pesci, director of communications, (919) 962-2600 or [email protected]

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