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People who have COPD are strongly advised to stop smoking - it's the "most important thing you can do".

The Center for Disease Control and Prevention states that the main problem is that the vast majority of secondhand smoke takes place inside job sites and homes

Higher wattage devices might deliver more nicotine per puff than lower wattage devices, even with the same e-liquid

[45] found that e-cigs have a powerful booster effect on phase-I carcinogen-bioactivating enzymes, including activators of polycyclic aromatic hydrocarbons (PAHs), and increase oxygen free radical production and DNA oxidation to 8-hydroxy2'-deoxyguanosine