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Further research evidence on NRT safety is needed, ideally from placebo-controlled RCTs that achieve higher adherence rates, monitor infants outcomes into childhood, and investigate higher doses of NRT than those tested in the included studies 1

Youth vaping has declined substantially since then, from 30-day prevalence of 27.5% in high school students in 2019 18 to 7.8% this year ( But the anxiety persists

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