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The body mounts an immune response to the prolonged irritation and oxidative stress from tobacco smoke that, over time, can lead to permanent changes to the lungs, including widening of the air sacs, excessive mucous secretion, and stiffening of the smaller airways [40]

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Cigarette smoking and changes in the histopathology of lung cancer

Meanwhile protein kinase-related pathways were activated, suggesting that the cells attempt to recover from the CS exposure

Together, the six otolaryngologists in this study helped to defend the tobacco industry in more than 50 cases