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Just as deep, however, was the later memory of disenfranchisement, deprivation of religious liberty and exclusion from public service effected by the penal laws

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In women, it may cause irregular menstrual cycles and lower estrogen levels, factors important for fertility and bone health

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These negative long-term effects of cocaine abuse include: cardiovascular damage from the drugs stimulant effects and an increased risk of chest pain, blood clots, heart attack, stroke, pulmonary embolism, deep vein thrombosis, tachycardia, arrhythmia, and other serious heart-related conditions recurrent seizures changes in personality, behavior, problem-solving, learning, and memory cerebral atrophy (brain shrinking) increased risk of developing various mental health disorders gastrointestinal issues including ulcers, ischemic colitis, and others liver damage or liver failure, especially in cases of combination alcohol and cocaine abuse kidney damage, including rhabdomyolysis (kidney damage related to other bodily tissue damage or death) reduced immune system functioning and increased risk of acquiring chronic diseases increased risk of serious dental issues premature aging Treatment Options For Cocaine Abuse And Addiction Unfortunately, many people underestimate just how habit-forming and addictive cocaine can be, especially when it comes to sniffing small doses with a coke bullet