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Nicotine increases plasminogen activator inhibitor-1 production by human brain endothelial cells via protein kinase C-associated pathway

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The plant has columnar shape with the characteristic heart-shaped leaf with a fringed petiole

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Negative effects of taking cannabis It may make you feel faint or sick It can make you sleepy and lethargic It can affect your memory It makes some people feel confused, anxious or paranoid, and some experience panic attacks and hallucinations It interferes with your ability to drive safely Source: NHS Choices In some cases cannabis can increase anxiety and paranoia, lead to confusion and even hallucinations, according to the Royal College of Psychiatrists