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Smoking increases oxidative stress and the excess reactive oxygen species (ROS) in cigarette smoke can activate orbital fibroblasts and promote fat expansion and fibrosis, all of which are key features of TED (6)

These findings hint at a broader capability of Ozempic to influence not just physical hunger but also various forms of psychological craving and addiction

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AIDS Behav 2017;21(7):19641974

Mediation analysis PROC CAUSALMED was used to conduct the mediation analysis

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