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Such dysregulation is frequently observed in tumor tissue and has been shown to play an essential role in tumor development (14,15)

For calculation and normalization of the probes oxidation degree at each time point, the means of all values recorded at all time points for R red , R ox , I 488 ox and I 488 red were used

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Owing to ethical considerations, few randomized controlled trials to prevent premature BPD have been conducted

The resulting DNA hypomethylation leads to changes in gene expression that underlie elements of the pathophysiology of ALD ( In contrast, histone methylation does not globally increase or decrease based on the methylation index

For imaging, two 40x images (160 m 160 m) were taken from the central area of each leaflet for each cohort