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What are the negative health effects of cigarette smoke

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Our data strongly suggest that cigarette smoking induces structural and functional changes in mitochondria resulting in a pro-inflammatory phenotype of airway epithelium in severe COPD patients, and that these are persistent, as they are still present upon smoking cessation

Thus, adipose tissue, an important regulator of the cardiovascular system (118, 119), produces bioactive factors that regulate lipid levels and is involved in inflammation, oxidative stress, and insulin resistance (120)

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