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We classified participants in the first enrollment period as one of the following: Never users : no current use of cigarettes or other tobacco products, smoked fewer than 100 cigarettes in their lifetime, and a urinary cotinine level below 10 ng/mL

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(Many e-liquid manufacturers don't even make flavors with regular nicotine at strengths over 6 mg/mL anymore.) Regular nicotine: 12-24 mg/mL Nicotine salts: 30-60 mg/mL Medium vapor production Clouds, but not of the massive variety

There is a difference between CBD and nicotine

Cardiovascular Health: Smoking is a major risk factor for cardiovascular diseases

Each of these ingredients has potential side effects that might cause a sore throat