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In the 2020 NSDUH, respondents were classified as having had a major depressive episode (MDE) in the past 12 months if (1) they had at least one period of 2 weeks or longer in the past year when for most of the day nearly every day, they felt depressed, or lost interest or pleasure in daily activities

While the bill has died in the legislature in recent years, it has bipartisan support, including from Senator Ann Rivers (R-LaCenter)

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Available evidence suggests that substance use may affect spermatogenesis, secretion of reproductive hormones through the hypothalamic-pituitary-gonadal (HPG) axis, and sexual function 31,32,33,34,35,36

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